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Stem Cells Explained

What are stem cells?

Amnion “stem cells” have a great capacity for self-renewal and regeneration in the human body.  This cellular fluid is minimally manipulated human tissue allografts derived from donors of live cesarean births.  This tissue is sourced through the university levels and has been screened for medical conditions and social histories.  The product is tested for sterility using procedures based on USP 71 sterility testing protocols.

Conditions regenerative stem cell therapy may help:

  1. Knee arthritis and injuries
  2. Hip arthritis
  3. Shoulder damage and repair
  4. Plantar fasciitis
  5. Low back pain and osteoarthritis
  6. Neck and cervical pain

Tell me more about these products:

The “healing” factors of amniotic tissue treatment are the growth factors found in the extracellular matrix of the amniotic tissue and well as remnant natural hyaluronic acid.

What about the FDA?

Our products are processed from the cesarean deliveries and regulated as a human cell or tissue-based product (HCT/P) under 21 CFR 1271 and Section 361 of the Public Health Service Act.

Where is this product used/injected?

Many utilize these services in joint and muscle tissue.  Best results are seen in joint health and muscle pain.  This includes knees, hips, shoulders.   For many years sports figures flew to Europe to receive these treatments.

Does your office utilize Platelet Rich Plasma (PRP)?

Yes, and with great success.

Our group:  Cellular Medical Association conducts 1,000 of research studies per year.

Can you explain PRP?

Platelet-rich plasma (PRP) is using your own cellular materials (oftentimes called adult stem cells) including cytokines, growth factors, and collagen.   It involves a blood draw to get your matrix material.  The most simple means to explain this product is:

“As a child, when one had a skinned knee, a yellow fluid came out while the knee was healing.”  The yellow product is what was healing the knee.  It contained all the growth factors, cytokines and healing mechanisms that the body requires to fully recover.

Why is your practice offering to have both amnion “stem cell” and platelet-rich plasma together?

Evidence shows us that both release healing factors.  Many cases to do not require both products together.  However, we recognized that we could offer these together to give our clientele an extra boost.

Most offices will do one procedure or the other.  We want to offer our patient population the ability to get both done at a very reasonable price.  We have done hundreds of procedures.  We have negotiated for the best pricing.  We want our patients to be given exactly what is needed. We want to ensure that cost is very affordable.  Unfortunately, some practices make these procedures cost prohibitive in the current market.  We also recognize that some research studies conclude that doing both together is a viable alternative to a surgical procedure (Rubio-Azpeitia, 2017)

What does the research state for knee injections for osteoarthritis?

A systematic review of Medline, Embase, Cochrane Central Register of Controlled Trials looked at the clinical efficacy of PRP and amnionic fluid to evaluate the therapeutic effect at 24 weeks.  The mean average age of participants was 51-years old and greater than 50% male (51.5%)  Those that received significant pain relief saw the greatest improvement at six months duration.

The conclusion stated that these type of injections favored the adult with mild to moderate osteoarthritis greater than six months.    Dr. Bryan Blake MD and Holly Ridgley NP   have seen this in their own patient population.

How many procedures has your office done?

Our office has done a large number of procedures.  Our specialty providers:   Dr. Bryan Blake MD and Holly Adams Ridgley  NP have trained with some of the best in the industry.   Ms.  Adams  Ridgley has also taught both PRP and amnion (stem cell therapy) in Arizona, Tennessee, and Pennsylvania to other provider groups on injection therapy.

What are PRP (platelet rich plasma) injections used for?

A PRP (platelet-rich plasma) injection is a technique that can be used to treat injured soft tissue. It can be used in combination with a surgical procedure or as a stand-alone treatment. Blood is drawn from the patient, then a centrifuge is utilized to separate the platelets from the blood.  The platelets contain the healing mechanism that works with the body to heal.

What differences are there between PRP and stem cell therapy?

While PRP may aid in the recruitment of stem cells to the area, amniotic stem cell injection therapy is much more advanced. Platelet-rich plasma (PRP) is similar to adding additional fertilizer and water to a plant, mesenchymal stem cells (MSC’s) are akin to placing new seeds in the area and hiring a landscaper.

Does your office offer consultations so I can meet my provider?

Absolutely!  Want to meet with our clientele to ensure their questions are answered.   We also want to determine what methodology works best for your treatment plan.

References:

  1. A. et al (2013). the efficacy of platelet-rich plasma in the treatment of symptomatic knee osteoarthritis: a systematic review with quantitative analysis. Arthroscopy, 2. Retrieved from https: www.ncbi.nlm.gov/pubmed/24286902

Rubio-Azpeitia, S. D. (2017). Adult Cells Combined with Platelet Rich Plasma for Tendon Healing. Orthopedic Sports Medicine, Rubio-Azpeitia, Sanchez, Delgado, Andia (February), 2. Retrieved February February 20, 2019, 2019, from http:www.ncbi.nlm.gov/pubmed/28321425

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